The state includes
t, the voltage for all segments of all sections, and all the STATEs defined in all the membrane and point process mechanisms. With regard to model descriptions, it does not include PARAMETERs, ASSIGNED variables. It always includes values for the ambiguous variable of ions such as cai, ko, or ena. This can be an expensive object in terms of memory storage.
The state also includes all the outstanding events (external and self) and the weight vectors of all NetCon objects. For model descriptions containing a NET_RECEIVE block, all the ASSIGNED variables are also included in the state (this is because such models often use such variables to store logic state and other values, such as the last event time t0, needed to compute state variables at the next event.)
The outstanding event delivery times are absolute. When restored, all outstanding events will be cleared and the restored event times and NetCon info will take their place. Note that it is not in general possible to change the value of t in a network simulation since most NET_RECEIVE blocks keep t0 (the last event time) as part of their state.
from neuron import h, rxd from neuron.units import mV, ms h.load_file("stdrun.hoc") soma = h.Section(name="soma") soma.insert(h.hh) soma.nseg = 51 cyt = rxd.Region(h.allsec(), name="cyt") c = rxd.Species(cyt, name="c", d=1, initial=lambda node: 1 if node.x < 0.5 else 0) c2 = rxd.Species( cyt, name="c2", d=0.6, initial=lambda node: 1 if node.x > 0.5 else 0 ) r = rxd.Rate(c, -c * (1 - c) * (0.3 - c)) r2 = rxd.Reaction(c + c2 > c2, 1) h.finitialize(-65 * mV) soma(0).v = -30 * mV h.continuerun(5 * ms) def get_state(): return ( soma(0.5).v, c.nodes(soma(0.5)).concentration, c2.nodes(soma(0.5)).concentration, ) s1 = get_state() # our local copy, just to prove we saved s = h.SaveState() s.save() # NOTE: calling s.save() stores the state to the s object; it does not # store the state to a file; use s.fwrite(file_obj) for that and # s.fread(file_obj) to read state from a file before restoring. h.continuerun(10 * ms) # go back to the way things were at 5 * ms (when we called s.save()) s.restore() # prove we successfully reverted assert get_state() == s1 assert get_state() != s2
Changed in version 8.1: Prior to NEURON 8.1,
SaveStatedid not save reaction-diffusion states.
The intention is that a save followed by any number of simulation-continue,restore pairs will give the same simulation result (assuming the simulation is deterministic). Given the possibility that simulations can be written to depend on a variety of computer states not saved in this object, this is more an experimental question than an assertion.
Between a save and a restore, it is important not to create or delete sections, NetCon objects, or point processes. Do not change the number of segments, insert or delete mechanisms, or change the location of point processes.
Does work with the local variable timestep method if the stdrun system is used since continuerun() uses cvode.solve(tstop) to integrate and this returns with all states at tstop. However, if you advance using fadvance() calls different cells will be at different t values in general and SaveState will be useless.
- t, voltage, state and event values are stored in the object.
t, voltage, state and event values are put back in the sections. Between a save and a restore, it is important not to create or delete sections, change the number of segments, insert or delete mechanisms, or change the location or number of point processes. Before restoring states, the object checks for consistency between its own data structure and the section structures.
If the arg is 1, then the event queue is not cleared and no saved events are put back on the queue. Therefore any Vector.play and/or FInitializeHandler events on the queue after finitialize() are not disturbed.
Reads binary state data from a File object into the SaveState object. (See File in ivochelp). This does not change the state of the sections. (That is done with
.restore()). This function opens the file defined by the File object. On return the file is closed unless the second arg exists and is 1.
Warning: file format depends on what mechanisms are available in the executable and the order that sections are created (and mechanisms inserted) by the user. Also the order of NetCon, ArtificialCell, PointProcess creation and just about everything else that gets saved in the file. I.e. if you change your simulation setup, old files may become incompatible.
- Opens the file defined by the File object, writes saved
binary state data to the beginning of the file.
On return the file is closed unless the second arg exists
and is 1. In that case, extra computer state information
may be written to the file, e.g.
- Writes saved state data as sequence of hoc statements that
can be read with
xopen(...). Not implemented at this time.